The product, formerly known as Filorga NCTF 135 HA, is produced by the French Fillmed Laboratory. Until 2018, the company was called Filorga Medical. On the occasion of the 40th anniversary of the organization, it was rebranded: the Filorga brand became Fillmed by Filorga. Under this brand, peelings, fillers (X-HA), preparations for biorevitalization (M-HA), and professional cosmetics are produced.

The NCTF (New Cellular Treatment Factor) formula is one of the manufacturer’s first developments. The line of mesococktails includes 3 multi-component products differing in the content of hyaluronic acid:

• NCTF 135 (2.5 mg/ml) – for young skin, up to 30 years old;
• NCTF 135 HA (5 mg/ml) for patients who have already noticed the first signs of skin withering, 30-35 years old;
• NCTF 135 HA+ (10 mg/ml) – for women and men older than 35 years old.

The polymer in NCTF 135 HA is identical to the hyaluronic acid found in the connective tissues of the body, and is therefore well accepted by the dermis. Non-cross-linked hyaluronic acid, thanks to its ability to attract and retain water, provides long-term hydration of tissues, maintaining the density and elasticity of the skin.

Other active components of the mesotherapy solution are:

• amino acids that activate fibroblasts and stimulate the synthesis of collagen and elastin;
• nucleic acids, which promote cell regeneration;
• coenzymes, accelerating the metabolism and reconstruction of tissues;
• antioxidants (vitamin C and glutathione), which role is to prevent oxidation of free radicals in the skin, preventing the destruction of cells under the influence of aggressive environmental factors;
• a complex of vitamins and minerals that strengthen blood vessels, have a whitening, revitalizing and anti-inflammatory effect.